Maciej D. Zatonski

According to the Centers for Disease Control and Prevention, during the 2016/2017 season influenza vaccines prevented an estimated 5.3 million influenza illnesses, 2.6 million influenza-associated medical visits, and at least 85,000 influenza-related hospitalisations in the United States (US) alone (...). And yet, the vast majority of countries, including most European Union (EU) states, fall short of the WHO vaccination target of 70% of the eligible population...

Risk resilience and the need for effectively managed compliance are more important today to the pharmaceutical industry than ever before. Pressures of markets, public expectations, the advancement of technology, and changing expectations of stakeholders require companies to
adapt to increasing numbers of risks. New information systems, strategies and processes to manage compliance are rapidly evolving in response to these pressures.

"It is not the strongest of the species that… Show more

Risk resilience and the need for effectively managed compliance are more important today to the pharmaceutical industry than ever before. Pressures of markets, public expectations, the advancement of technology, and changing expectations of stakeholders require companies to
adapt to increasing numbers of risks. New information systems, strategies and processes to manage compliance are rapidly evolving in response to these pressures.

"It is not the strongest of the species that survives, nor the most intelligent that
survives. It is the one that is most adaptable to change." – C. R. Darwin Show less

To evaluate the impact of selecting treatment for nasal obstruction on the basis of a structured physiology-based assessment protocol on patient outcomes. Prospective Longitudinal Study.

Psychology Gone Wrong: The Dark Sides of Science and Therapy explores the dark sides of psychology, the science that penetrates almost every area of our lives. It must be read by everyone who has an interest in psychology, by all those who are studying or intend to study psychology, and by present and potential clients of psychotherapists. This book will tell you which parts of psychology are supported by scientific evidence, and which parts are simply castles built on sand. This is the first… Show more

Psychology Gone Wrong: The Dark Sides of Science and Therapy explores the dark sides of psychology, the science that penetrates almost every area of our lives. It must be read by everyone who has an interest in psychology, by all those who are studying or intend to study psychology, and by present and potential clients of psychotherapists. This book will tell you which parts of psychology are supported by scientific evidence, and which parts are simply castles built on sand. This is the first book which comprehensively covers all mistakes, frauds and abuses of academic psychology, psychotherapy, and psycho-business. Show less

...historically, we were not able to pick those things early enough. The tumor had to be of a size that would be detectable with our fin- gers or eyes—and it often meant that it was too late for a cure. We have learned to look inside our bodies to identify tiny lumps that are invisible to the eye and impossible to feel or touch. Later came newer technologies that allowed us to spot abnormalities in tissues, cells, and even on the molecular level. We thought that this is good, because every… Show more

...historically, we were not able to pick those things early enough. The tumor had to be of a size that would be detectable with our fin- gers or eyes—and it often meant that it was too late for a cure. We have learned to look inside our bodies to identify tiny lumps that are invisible to the eye and impossible to feel or touch. Later came newer technologies that allowed us to spot abnormalities in tissues, cells, and even on the molecular level. We thought that this is good, because every advanced disease had to start early. But it all came at a price... Show less

ISBN 978-1-60876-107-4

ISBN 978-953-307-079-7

Different types of cells require activation, and take part in annual, dynamic growth of deer antlers. Stem cells play the most important role in this process. This report shows the results of a two-year long observation of xenogenic implant of antlerogenic stem cells (cell line MIC-1). The cells were derived from growing antler of a deer (Cervus elaphus), seeded onto Spongostan and placed in postoperative lesions of mandibular bones of 15 experimental rabbits. The healing process observed in… Show more

Different types of cells require activation, and take part in annual, dynamic growth of deer antlers. Stem cells play the most important role in this process. This report shows the results of a two-year long observation of xenogenic implant of antlerogenic stem cells (cell line MIC-1). The cells were derived from growing antler of a deer (Cervus elaphus), seeded onto Spongostan and placed in postoperative lesions of mandibular bones of 15 experimental rabbits. The healing process observed in the implantation sites in all rabbits was normal, and no local inflammatory response was ever observed. Histological and immunohistochemical evaluations were performed after 1, 2, 6, 12 and 24 months, and confirmed the participation of xenogenic cells in the regeneration processes, as well as a lack of rejection of the implants. The deficiencies in the bones were replaced by newly formed, thick fibrous bone tissue that underwent mineralization and was later remodelled into lamellar bone. The results of the experiment with rabbits allow us to believe that antlerogenic cells could be used in reconstruction of bone tissues in other species as well. Show less

The diagnosis of laryngeal lesions with standard imaging techniques relies strongly on the clinical experience of the examiner in recognizing suspicious mucosal pathology. It is well known that early detection and accurate determination of the localization and extent of those changes are crucial for further therapy and patient prognosis. Therefore, attempts to optimize diagnostic procedures to achieve more sensitive detection and accurate description are constantly made. Promising techniques… Show more

The diagnosis of laryngeal lesions with standard imaging techniques relies strongly on the clinical experience of the examiner in recognizing suspicious mucosal pathology. It is well known that early detection and accurate determination of the localization and extent of those changes are crucial for further therapy and patient prognosis. Therefore, attempts to optimize diagnostic procedures to achieve more sensitive detection and accurate description are constantly made. Promising techniques that have been developed to gain more information about the biologic character of a lesion are autofluorescence (AFE) and contact endoscopy (CE). The aim of this chapter is to describe the authors‘ experiences with both AFE and CE techniques in oncological diagnosis. Show less

Regenerative medicine in the recent years aims at explaining involvement of stem cells in regenerative processes and applying this knowledge in fulfilling human needs to find new, more efficient therapeutic methods. Growing antlers constitute a model organ for examining regeneration processes of tissues because they are the only mammalian appendages capable of regeneration. The rate of growth of deer antlers makes them one of the quickest growing structures in mammals. The cells taking part in… Show more

Regenerative medicine in the recent years aims at explaining involvement of stem cells in regenerative processes and applying this knowledge in fulfilling human needs to find new, more efficient therapeutic methods. Growing antlers constitute a model organ for examining regeneration processes of tissues because they are the only mammalian appendages capable of regeneration. The rate of growth of deer antlers makes them one of the quickest growing structures in mammals. The cells taking part in this process have a considerable proliferating potential. The aim of the study was to analyze the possibility of using xenogenous antlerogenic cells (AC) in regeneration of cartilaginous tissues in non-immunosuppressed animals. Show less